Parsons J., Francavilla C.*'Omics Approaches to Explore the Breast Cancer Landscape.(2020).Front Cell Dev Biol..Jan 22;7:395. doi: 10.3389/fcell.2019.00395. eCollection 2019. Review.
Pearson A. J., Fullwood P., Toro Tapia G., Prise I., Smith M.P., Xu Q., Jordan A., Giurisato E., Whitmarsh A.J., Francavilla C., Tournier C..Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5).(2020).Int J Mol Sci. .Jan 31;21(3). pii: E929. doi: 10.3390/ijms21030929.
Hamilton W. B., Mosesson Y., Monteiro R.S., Emdal K. B., Knudsen T.E., Francavilla C., Barkai N., Olsen J.V., Brickman J.M..Dynamic lineage priming is driven via direct enhancer regulation by ERK.(2019).Nature.Nov;575(7782):355-360. doi: 10.1038/s41586-019-1732-z. Epub 2019 Nov 6.
Lundby A., Franciosa G., Emdal K.B., Refsgaard J.C., Gnosa S. P., Bekker-Jensen D.B., Secher A., Maurya S. R., Paul I., Mendez B.I., Kelstrup C.D., Francavilla C., Kveilborg M., Montoya G., Jensen L.J., Olsen J.V..Oncogenic mutations rewire signaling pathways by switching protein recruitment to phosphotyrosine sites .(2019).Cell.Oct 3;179(2):543-560.e26. doi: 10.1016/j.cell.2019.09.008.
Zamai M., Trullo A., Giordano M., Corti V., Cuesta E. A., Francavilla C., Cavallaro U., Caiolfa V. R..Number and brightness analysis in live cells reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1.(2019).J Cell Sci .Jan 3;132(1). pii: jcs220624. doi: 10.1242/jcs.220624.
Emdal K. B., Pedersen A. K., Bekker-Jensen D. B., Lundby A., Claeys S., De Preter K., Speleman F., Francavilla C.*#, Olsen J. V.*#. #, equal senior contributionIntegrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma.(2018).Sci Signal.Nov 20;11(557).
Watson J., Francavilla C.*Regulation of FGF10 Signaling in Development and Disease.(2018).Front Genet.Oct 23;9:500.
Batth T.S., Papetti M., Pfeiffer A., Tollenaere M.A.X., Francavilla C.*, and Olsen J.V.*.Large-scale phosphoproteomics reveals Shp2 phosphatase-dependent regulators of Pdgf receptor signaling.(2018).Cell Rep.Mar 6;22(10):2784-2796.
Sanchez-Quiles V., Akimov V., Osinalde N., Francavilla C., Puglia M., Barrio-Hernandez I., Kratchmarova I., Olsen J.V., Blagoev B..Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor.(2017).Mol Cell Proteomics. Aug;16(8):1433-1446.
Francavilla C.*, Lupia M., Tsafou K., Villa A., Kowalczyk K., Rakownikow Jersie-Christensen R., Bertalot G., Confalonieri S., Brunak S., Jensen L.J., Cavallaro U.*, Olsen J.V.*.Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer.(2017).Cell Rep. Mar 28;18(13):3242-3256.
Francavilla C.*, Papetti M., Rigbolt T.G., Pedersen A-K., Sirurdson J.O., Cazzamali G., Karemore G., Blagoev B., Olsen J.V.*.Multi-layered Proteomics reveals Molecular Switches Dictating Ligand-dependent EGFR Trafficking.(2016).Nat. Struct. Mol. Biol. 23(6):608-18.
Von Stechow L., Francavilla C., Olsen J.V.Recent findings and technological advances in phopshoproteomics for cells and tissues.(2015).Expert. Rev. Proteomics.12(5): 469-487.
Satpathy S., Wagner S.A., Beli P., Gupta R., Kristiansen T.A., Malinova D., Francavilla C., Tolar P., Bishop G.A., Hostager B.S., Choudhary C Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.(2015).Molecular systems biology.11(6): 810 (Highlighted in the Editors' Choice section of Science Signaling: B cell receptor signaling dynamics, Sudhakaran Prabakaran, (2015) Sci Signal. 8, Issue 384, pp. ec186).
Emdal K.B., Pedersen A.K., Bekker-Jensen D.B., Tsafou K.P., Horn H., Lindner S., Schulte J.H., Eggert A., Jensen L.J., Francavilla C.*#, Olsen J.V.*#.#, equal senior contributionTemporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation.(2015).Science signaling. 8(374): ra40 (Featured with the cover image).
Batth T.S., Francavilla C., Olsen J.VOff-line high-pH reversed-phase fractionation for in-depth phosphoproteomics.(2014).Journal of proteome research.Dec 5, 13(12): 6176-86.
Francavilla C., Hekmat O., Blagoev B., Olsen J.VSILAC-based temporal phosphoproteomics.(2014).Methods Mol Biol.Jul, 1188: 125-48.
Schimmel J., Eifler K., Sigurethsson J.O., Cuijpers S.A., Hendriks I.A., Verlaan-de Vries M., Kelstrup C.D., Francavilla C., Medema R.H., Olsen J.V., Vertegaal A.C.Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.(2014).Molecular cell..Mar 20, 53(6): 1053-66.
Petersen D.L., Krejsgaard T., Berthelsen J., Fredholm S., Willerslev-Olsen A., Sibbesen N.A., Bonefeld C.M., Andersen M.H., Francavilla C., Olsen J.V., Hu T., Zhang M., Wasik M.A., Geisler C., Woetmann A., Odum N. B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with dasatinib in cutaneous T-cell lymphoma (CTCL).(2014).Leukemia.Oct, 28(10): 2109-12.
Radhakrishnan P., Dabelsteen S., Madsen F.B., Francavilla C., Kopp K.L., Steentoft C., Vakhrushev S.Y., Olsen J.V., Hansen L., Bennett E.P., Woetmann A., Yin G., Chen L., Song H., Bak M., Hlady R.A., Peters S.L., Opavsky R., Thode C., Qvortrup K., Schjoldager K.T., Clausen H., Hollingsworth M.A., Wandall H.H. Immature truncated O-glycophenotype of cancer directly induces oncogenic features.(2014).Proceedings of the National Academy of Sciences of the United States of America.Sep 30, 111(39): E4066-75.
Lundby A., Andersen M.N., Steffensen A.B., Horn H., Kelstrup C.D., Francavilla C., Jensen L.J., Schmitt N., Thomsen M.B., Olsen J.V. In vivo phosphoproteomics analysis reveals the cardiac targets of beta-adrenergic receptor signaling.(2013).Science signaling.Jun 4, 6(278): rs11.
Galli G.G., Carrara M., Francavilla C., de Lichtenberg K.H., Olsen J.V., Calogero R.A., Lund A.H. Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells.(2013).Molecular and cellular biology.Nov, 33(22): 4504-16.
Hekmat O., Munk S., Fogh L., Yadav R., Francavilla C., Horn H., Wurtz S.O., Schrohl A.S., Damsgaard B., Romer M.U., Belling K.C., Jensen N.F., Gromova I., Bekker-Jensen D.B., Moreira J.M., Jensen L.J., Gupta R., Lademann U., Brunner N., Olsen J.V., Stenvang J. TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells.(2013).Journal of proteome research.Sep 6, 12(9): 4136-51..
Francavilla C., Rigbolt K.T., Emdal K.B., Carraro G., Vernet E., Bekker-Jensen D.B., Streicher W., Wikstrom M., Sundstrom M., Bellusci S., Cavallaro U., Blagoev B., Olsen J.V.Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs..(2013).Molecular cell.Sep 26, 51(6): 707-22 (Highlighted in the Editors' Choice section of Science Signaling: Dictating the Route, Nancy R. Gough, (2013) Sci Signal. 6, Issue 295, pp. ec236).
Kelstrup C.D., Hekmat O., Francavilla C., Olsen J.V. Pinpointing phosphorylation sites: Quantitative filtering and a novel site-specific x-ion fragment.(2011).Journal of proteome research.Jul 1, 10(7): 2937-48.
Murakami M., Francavilla C., Torselli I., Corada M., Maddaluno L., Sica A., Matteoli G., Iliev I.D., Mantovani A., Rescigno M., Cavallaro U., Dejana E. nactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration.(2010).Cancer research.Mar 1, 70(5): 1759-65.
Monegal A., Ami D., Martinelli C., Huang H., Aliprandi M., Capasso P., Francavilla C., Ossolengo G., de Marco A. Immunological applications of single-domain llama recombinant antibodies isolated from a naive library.(2009).Protein engineering, design & selection : PEDS.Apr, 22(4): 273-80.
Francavilla C., Cattaneo P., Berezin V., Bock E., Ami D., de Marco A., Christofori G., Cavallaro U. The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking.(2009).The Journal of cell biology.Dec 28, 187(7): 1101-16.
Francavilla C.#, Maddaluno L.#, Cavallaro U. #, equal contribution he functional role of cell adhesion molecules in tumor angiogenesis..(2009).Seminars in cancer biology..Oct, 19(5): 298-309.
Francavilla C., Loeffler S., Piccini D., Kren A., Christofori G., Cavallaro U. Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor.(2007).Journal of cell science.Dec 15, 120(Pt 24): 4388-94.
* corresponding author