Signalling in three-dimensional cell culture

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three dimensional cell culture, breast cancer, adipocytes, epithelial cells, omics, single cell analyses, data integration, drug screening, skin models, organoids

Breast cancer cell spheroids

The complexity of signalling architecture depends on components of the cell microenvironment. This project aims at understanding how growth factors signalling is affected by the changing microenvironment. We combine cell culture in 3D with omics technologies and validation of results in patient-derived samples

Chiara Francavilla

Since July 2023 Chiara is Associate Professor at DTU Bioengineering, Danish Technical University, Denmark, and an honorary Senior Research Fellow at the University of Manchester, United Kingdom.

pubblications biography

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System biology analysis of FGFR and EGFR signaling in breast cancer
Multiomics analysis of breast cancer metastasis in silico, in vitro, and in vivo
Global and local cellular signaling